Andrei Vasilevskiy made 29 saves as the Lighting skated to a 3-1 win over the Red Wings in Tampa Bay.
Alex Killorn, Steven Stamkos and Brayden Point scored for the Lightning.
The Lightning have won three in a row to boost their record to 4-1-and-0.
Luke Glendening scored the lone Detroit goal to tie the game at one in the second.
Jimmy Howard allowed two goals on 30 shots in defeat.
The Wings are still winless on the season at 0-5-and-2 and they play the Panthers Saturday night in Sunrise.