After nearly eight hours, Highway 3 in Essex is now open between Victoria Ave. in Essex after a two vehicle crash.
The crash happened just after 12 p.m. on Friday.
OPP Constable Jim Root says two people were sent to hospital with one person suffering life threatening injuries.
Root says it was a head-on collision and one of the drivers fled the area.
"The lone occupant and driver of the second vehicle according to witnesses left the scene on foot prior to police arrival," he says.
Anyone with information is asked to call the OPP.
"We're hoping anyone that was in this area and observed this collision or anything else at that time could contact OPP at 1-888-310-1122 to assist us in this investigation," says Root.