A chain-reaction crash caused Highway 3 in Kingsville to be closed for a few hours Wednesday morning
The OPP say a four-vehicle crash started with a truck rear-ending another vehicle.
The eastbound truck forced the other vehicle into the oncoming westbound lanes where it struck a third vehicle.
The truck continued east, striking another vehicle before veering into the ditch.
Police were called around 8:30am to the highway between Belle River Rd. West and Division Rd.
Two of the injured people are being treated in hospital with non-life threatening injuries, the others suffered minor injuries.
Police are continuing to investigate the crash.