The Detroit Tigers fell to the Twins 9-3 in Minnesota in Major League Baseball.
Starter Francisco Liriano left Thursday's game early with tightness in his back.
He was charged with the loss after giving up four runs in less than three innings.
Jeimer Candelario, Nicholas Castellanos and Christin Stewart each had an RBI.
Detroit begins the last series of the season Friday night against the Brewers in Milwaukee.
Jordan Zimmermann goes to the mound for the Tigers and Zach Davies gets the nod for the Brewers.
Milwaukee is playoff bound, but still fighting for the NL Central title.