Chris Bassitt and two relievers combined on a three-hitter as the Athletics shut out the Tigers 3-0 in Detroit.
Bassitt allowed two hits over six innings for his first win of the season.
Jed Lowrie doubled in a run in the fourth, and Josh Phegley and Dustin Fowler had RBI doubles in the ninth as Oakland won its third straight.
Mike Fiers allowed one run in seven innings to take the tough-luck loss.
Nicholas Castellanos, John Hicks and Jose Iglesias had hits for Detroit, which has dropped its eighth in-a-row.
In this afternoon's series finale, Michael Fulmer gets the start for Detroit, while Oakland sends Sean Manaea to the mound.