Jed Lowrie hit a tiebreaking solo homer in the top of the ninth inning to lift Oakland to a 5-4 victory over the Detroit Tiger.
Edwin Jackson allowed a run and six hits in six innings in his first appearance for the A's.
The A's have now won seven of nine.
Jordan Zimmermann pitched five scoreless innings for the Tigers.
The two teams will meet again at Comerica Park, tomorrow night at 7:10.
— with files from The Canadian Press