The Tigers and Pirates met for a doubleheader Sunday to close out their season-opening series at Comerica Park.
Trevor Williams and three relievers combined for a two-hit shutout as the Pirates blanked the Tigers 1-0 in the opener.
Williams was pulled six innings into a no-hitter and came away with the win. Felipe Rivero struck out the side in the ninth for his first save.
Michael Fulmer yielded the one run on four hits over eight frames to suffer the tough-luck loss for Detroit.
The Pirates then rallied for five runs in the fifth inning and held on to edge the Tigers 8-6 in the second game of their doubleheader in Detroit.
David Freese hit a two-run homer to cap the five-run frame for Pittsburgh.
Tigers starter Ryan Carpenter lasted just three innings in his Major League debut. Buck Farmer surrendered five runs over two frames of relief to take the loss.
Miguel Cabrera homered and had an RBI double as the Tigers fell to 0-and-3.