AJ Spellacy and Liam Greentree each scored twice to lead the Spitfires to a 5-1 win over the Erie Otters at the WFCU Centre Thursday night.
Joey Costanzo made 24 saves to pick up the win.
The Spitfires open a home-and-home series against the top-ranked junior team in London Friday night.
The two teams will meet again Saturday night in Windsor.
The Knights lead the Spitfires by one point for first-place in the OHL Western Conference.
AM800's coverage with Steve Bell begins with the pre-game show at 6:45pm.