Michael Rasmussen and Andreas Athanasiou scored and Harri Sateri made 29 saves as the Red Wings defeated the Pittsburgh Penguins 3-2.
The Red Wings, playing four NHL games in five days, improved to 4-0.
Trevor Daley scored what proved to be the winning goal at 9:54 of the second period, capping a run that saw his team scored three times in a span of 5:47.
Rasmussen tied it at 1-1 at 4:07 of the second and Athanasiou scored at 6:07.
Ryan Haggerty and Teddy Blueger scored for the Penguins.
The Red Wings outshot the Penguins 33-31.
The Red Wings skate in Chicago on Tuesday.