The Red Sox built a seven-run lead in the sixth inning as they hammered the Blue Jays 10-5 in Toronto.
Xander Bogaerts finished with three RBI and Rafael Devers tagged a two-run homer for Boston.
Brian Johnson worked seven innings for the win, Boston's sixth in-a-row.
At 81-and-34, the Red Sox sit nine games ahead of New York in the AL East.
Blue Jays starter Mike Hauschild was chased in the third inning and took the loss.
Teoscar Hernandez and Randall Grichuk homered in defeat.
Ryan Borucki gets the start for the Jays as they close out their three-game set at Rogers Centre.
Rick Porcello takes the mound for the A-L East leading Red Sox.