DeMar DeRozan scored 16 points as the Raptors routed the Celtics 96-78 in Toronto.
The Raptors outscored the Celtics 29-13 in the second quarter to take a 10-point halftime lead.
Fred VanVleet and Serge Ibaka chipped in with 15 points apiece as Toronto snapped a two-game slide.
The Raptors hold a three-game lead over the Celtics for the East lead with four games to play.
Marcus Morris paced the C's with 21 points and Greg Monroe added 17.
Boston has dropped two in-a-row after winning its previous six.