The Pistons remain unbeaten at the Palace after dropping the Thunder 10488.
Tobias Harris led the way with 22 points as the Pistons topped the Thunder 104-88 in Auburn Hills.
Detroit center Andre Drummond missed the game with a sprained ankle but his replacement Aron Baynes filled in with 20 points and eight boards.
The Pistons' defense held the Thunder to 37-point-five percent shooting as they improved to 6-and-5.
The Pistons are at the Knicks tomorrow.
Russell Westbrook was the only bright spot for Oklahoma City with 33 points, 15 rebounds, and eight assists. The Thunder fell to 6-and-5 after their fourth-straight loss.