Tobias Harris poured in 25 points and Avery Bradley had 24 as the Pistons defeated the Heat 112-103 in Detroit.
Reggie Jackson added 17 points, while Andre Drummond hauled in 17 rebounds and scored eight points.
Rookie Luke Kennard finished with a career-high 14 points.
Detroit won its fifth straight and at 10-and-3 is off to its best start since 2005.
Hassan Whiteside led the Heat with 20 points and a dozen boards.
Goran Dragic had 18 points and seven assists for the Heat.
The Pistons play Wednesday in Milwaukee.