Matthew Stafford threw a pair of touchdown passes and the Detroit Lions ran for 248 yards as a team in a 32-21 win over the Dolphins in Miami.
Kerryon Johnson had 19 carries for 158 yards, while LeGarrette Blount added 50 yards and a score on 10 touches on Sunday.
Stafford finished 18-of-22 for 217 yards and the two TD's, both to Michael Roberts, as Detroit evened its NFL record at 3-and-3.
Brock Osweiler started in place of injured starter Ryan Tannehill for the second straight week and threw for 239 yards and two scores for Miami.
Kenyan Drake ran for 72 yards and a TD in the setback.
The Dolphins are now 4-and-3 after starting the season 3-and-0.