The Leafs win in Edmonton 42 for their second road win of the season.
Auston Matthews scored his 10th goal of the season as the Toronto Maple Leafs beat the Edmonton Oilers 4-2 on Tuesday for just their second road win of the season.
James van Riemsdyk, Nazem Kadri and Zach Hyman also scored for the Maple Leafs (10-8-4), who have won two straight.
Connor McDavid and Andrej Sekera responded for the Oilers (12-10-2), who have lost three games in a row.
Leafs goalie Frederik Andersen made 12 first-period saves, including a huge glove save to rob Leon Draisaitl in tight.
The Leafs are in Calgary tonight.