Jakob Junis pitched his first career complete game as the Royals topped the Tigers 6-2 in Kansas City.
Junis allowed six hits, struck out seven and walked none.
Adalberto Mondesi homered and Hunter Dozier had a two-run double for Kansas City, which is 3-and-1 on this homestand.
Matthew Boyd took the loss, yielding five runs over six innings.
JaCoby Jones homered in the eighth for Detroit, which has lost four straight.
Michael Fulmer is scheduled to get the start for Detroit and Danny Duffy for Kansas City in this afternoon's two-game series finale.