Investigators are back on the scene after a fire at Hogan's Printing on Tecumseh Rd. East at Lincoln.
They're trying to determine the cause of the blaze that broke out early Sunday morning.
Windsor police along with Windsor fire and two investigators with Ontario Fire Marshal's Office are on the scene.
The roof of the printing shop did collapse and the business sustained significant damage.
Chief Fire Prevention Officer John Lee believes damages will top $500,000.
The bank next door had smoke and water damage, while a neighbouring dress shop had smoke damage.
This was the second time a fire hit Hogan's Printing.
15 months ago, the business suffered heavy damage when it was located on Drouillard Road.