Jake Guentzel racked up four goals including a hat trick in the third period alone, as the Penguins advanced to the second round of the playoffs with an 8-5 rout of the Flyers in Philadelphia.
Sidney Crosby had a goal and two assists for the Pens, who win the best-of-seven quarterfinal series four-games-to-two.
Sean Couturier racked up three goals and two helpers for the Flyers while playing with a torn MCL.
The two-time defending Stanley Cup champion Penguins will face the winner of the Washington-Columbus series. Game 6 of that series will be played Monday in Columbus with the Capitals up 3-games-to-2.