Kentucky Derby favourite Omaha Beach has been scratched from Saturday's race because of a breathing problem.
The colt from Southern California was made the 4-to-1 early favourite for the 145th Derby.
Omaha Beach galloped Wednesday morning without any problems, and trainer Richard Mandella said everything was fine. But that changed by late afternoon when Mandella said the horse has an entrapped epiglottis.
Churchill Downs oddsmaker Mike Battaglia revised the morning line to make Game Winner the 9-to-2 favourite for the 1-and-a-quarter-mile race.