The Los Angeles Dodgers will begin defense of their World Series title in Colorado on April 1.
ESPN announced the game will be part of an Opening Day quadruple-header broadcast by the network.
The New York Yankees and Toronto Blue Jays start things off, followed by the Dodgers-Rockies at Coors Field.
The New York Mets and Washington Nationals will square off in DC, while the Astros and A's play in Oakland.
With files from the Associated Press