Rowdy Tellez and Randal Grichuk plated runs in the eighth inning to lift the Blue Jays past the Yankees 3-2 in New York.
Reese McGuire doubled in the other run in the third for Toronto, which took two-of-three in the series.
Thomas Pannone tossed seven innings of two-run ball for the win. Ken Giles closed it out for his 22nd save.
Andrew McCutchen homered and Didi Gregorius plated one during a two-run first for the Yankees, who hold the top AL Wild Card at 91-and-58.
Dellin Betances took the loss.