Thomas Pannone took a no-hitter into the seventh inning in his first major league start and Devon Travis hit a three-run homer as the Blue Jays downed the Baltimore Orioles 6-0.
Pannone (1-0) allowed just one hit while striking out three and walking two in a 108-pitch, seven-inning performance.
He lost his no-hit bid when Trey Mancini singled to lead off the seventh on his 91st pitch of the game, an 81 mile-per-hour changeup.
The 24-year-old left-hander walked off the mound to a loud ovation from the 40,595 in attendance for the afternoon start.
Toronto's offence ensured Pannone the win, scoring five runs in the eighth inning before Baltimore recorded a single out.
The barrage was capped by Travis's three-run shot off reliever Miguel Castro, a former Blue Jays prospect.